On May 11, 1998, about 1820 eastern daylight time, a Cessna 310Q, N7795Q, was destroyed during a collision with terrain on final approach to Boire Field Airport (ASH), Nashua, New Hampshire. The certificated airline transport pilot was seriously injured. Visual meteorological conditions prevailed and an instrument flight rules flight plan was filed for the ferry flight conducted under 14 CFR Part 91. According to a Federal Aviation Administration (FAA) Inspector, the airplane was refueled at Charleston Yeager Airport (CRW), Charleston, West Virginia on Thursday, May 7, 1998, with 76.8 gallons of fuel to fill the tanks to 163 total gallons. The airplane then flew from CRW to Benedium Airport (CKB), Clarksburg, West Virginia, approximately a 40 minute flight. The airplane remained on the ramp until Monday, May 11, 1999, when it departed CKB for ASH. The flight departed Benedium Airport at 1510, arrived in the Nashua area with no reported problems, and was cleared for the Instrument Landing System (ILS) approach to runway 14 at ASH. The pilot reported the runway in sight, and was cleared to land on runway 14. The pilot requested a wind check, and after the controller's response, stated that "it seems a little worse here." Shortly thereafter, the controller reported that the airplane disappeared into the trees. A witness, who was waiting for the airplane to arrive, stated that "the airplane appeared a little lower than normal, and all of a sudden, the airplane just dropped out of sight." A witness working at the airport observed the approach of the airplane. He stated that the airplane appeared to be "right of the centerline." He further stated "at about 200 feet above the trees, the aircraft's descent rate increased considerably and descended wings level into the trees." The airplane was found 1 1/2 miles from the end of the runway 14 and approximately 150 feet to the right of the glide path centerline. Both wing tip tanks, the left wing from the engine nacelle outboard, and the empennage were separated from the fuselage. The fuselage came to rest approximately 100 feet from the first contact with trees, on a heading of 330 degrees. Flight control continuity was confirmed to the wing and empennage separation areas. No evidence of pre-impact damage was observed in the engines. The propeller blades sustained impact damage, but minimal scratching. The FAA Inspector reported that there was a "minimal smell of fuel throughout the wreckage area." The airplane was equipped with two main (tip) fuel tanks, two auxiliary fuel tanks, one on each wing, and a wing locker fuel tank on the right nacelle. Examination by an FAA Inspector revealed, both main tanks and both auxiliary tanks were ruptured, and there was "no evidence of fuel" (liquid, fumes, or vegetation burn damage) in the vicinity of these tanks. Approximately 11 1/2 gallons of fuel was drained from the right wing locker fuel tank. The fuel controls for both engines displayed no fuel and the fuel screens were clean. The spark plugs for all cylinders were clean and dry. The left engine fuel selector valve was in the left auxiliary position and the valve in the wing corresponded with this position. The right engine fuel selector valve was in the left main position; however, the right wing fuel valve was found in the right main position and the push pull rod was bent at the point of tree impact damage on the wing. The wing locker fuel transfer switch was found in the OFF position. According to the Cessna 310 Owner's Manual, "...Since part of the fuel from the auxiliary tanks is diverted to the main tanks instead of being consumed by the engines, the auxiliary tanks will run dry sooner than anticipated. The auxiliary tanks are designed for cruising flight, and are not equipped with pumps and are not recommended for use near the ground." The manual further stated "...the wing locker fuel is pumped directly into the main tanks with a fuel transfer pump, and the wing locker fuel should not be transferred until there is 180 pounds or less in the main fuel tanks to prevent overflow of the main fuel tank. The transfer pump should be tuned ON only to transfer fuel and turned OFF when the fuel has been transferred." The Cessna 310 Owner's Manual stated that the endurance for the airplane at 75% BHP, an altitude of 9,000 feet and with 978 pounds of fuel onboard, was 4.75 hours. At 65% BHP, the endurance was 5.3 hours. In a statement to an FAA Inspector, the pilot said he "does not recall anything about the flight"; however, he stated that his normal procedure for long flights was to "take off on the main tanks, switch to the auxiliary tanks, and land on the main tanks." He further stated that he received his multi-engine rating in the Cessna 310 in 1974, and that he had most of his time in the airplane in the 70's or early 80's. The pilot stated the last time he flew this airplane (make and model) was in the late 80's or possible early 1990. A special weather observation was reported at 1820, at Boire Field, which indicated variable winds from 010 to 120 degrees at 5 knots, gusting to 12 knots. The observation also contained light rain in progress. At 1855, winds were reported from 340 degrees at 5 knots. The ILS was flight checked by the FAA and found to be within operational limits. The pilot reported approximately 8,000 total flight hours, 165 hours of which were in this make and model.