On July 8, 2000, about 1045 Eastern Daylight Time, a Cessna 206, N5316U, was substantially damaged while landing at the Lee Airport (ANP), Annapolis, Maryland. The certified commercial pilot received minor injuries, and his passenger received serious injuries. Visual meteorological conditions prevailed for the personal flight, which originated at the Martin State Airport, Baltimore, Maryland. No flight plan was filed for the flight conducted under 14 CFR Part 91. During a telephone interview, the pilot stated that he entered the traffic pattern at ANP and prepared for a landing on Runway 30, a 2,505 foot long runway. He extended the first notch of flaps at 140 knots, and the second and third notches below 100 knots. The pilot initiated a "slip" on final approach, when he realized his approach speed was "too fast." He noted that the last time he looked at the airspeed indicator, it read 120 knots. At the point of touchdown, the airplane was "still traveling too fast," and "ran out of runway." The airplane traveled off the departure end of the runway and came to rest upside down. The pilot stated the accident occurred because of "pilot error," and could have been avoided if he had performed a go-around, instead of attempting to land. The pilot reported to a Federal Aviation Administration (FAA) inspector that he "messed up the landing" by landing "long and fast." Witnesses at the scene of the accident reported to the FAA inspector that the airplane touched down on the last quarter of the runway, ran off the end, and rolled over onto its back. Examination of the airplane by an FAA inspector revealed substantial damage to the rudder, vertical stabilizer, fuselage, and both main wing spars. Additionally, the firewall and engine mounts were bent. The pilot reported 2,180 hours of total flight experience, of which 1,200 hours were in the make and model of the accident airplane. The winds reported at an airport 25 miles away, at 1054, were from 320 degrees at 3 knots. According to the Cessna 206G Pilot's Operating Handbook, the recommended airspeed for a normal landing is 65-75 KIAS (flaps DOWN). Additionally, examination of the Landing Distance Chart revealed that the airplane would have needed approximately 1,429 feet of landing distance to clear a 50 foot obstacle at the approach end of the runway. This performance chart assumed the airplane was landing with 40 degrees of flaps, idle power, and zero wind.