On April 10, 2002, at 0428 central daylight time, a Cessna 172N, N733PX, piloted by a private pilot, sustained substantial damage when it impacted terrain after it went off the left side of runway 21 (7,001 feet by 150 feet, concrete), at the Outagamie County Regional Airport, Appleton, Wisconsin. The airplane was on the takeoff roll at the time of the accident. The pilot, who was the sole occupant, was not injured. The 14 CFR Part 91 personal flight was operating in visual meteorological conditions and was not on a flight plan. The intended destination was the Fond Du Lac County Airport, Fond Du Lac, Wisconsin. The pilot reported that during takeoff, "the aircraft began pulling [to the] left. Executed right rudder inputs to correct. No effect." The airplane subsequently exited the runway. A postaccident examination was conducted. The nose and right main landing gears were torn loose from the airframe. The right wing and horizontal stabilizer were damaged. No anomalies were found with respect to the airplane, or its systems, that could be associated with a pre-impact condition.