On August 9, 2013, about 1315 central daylight time, an experimental Long EZ airplane, N721EZ, departed from the runway surface while landing at the Schaumburg Regional Airport (06C), Schaumburg, Illinois. The private pilot was not injured and the airplane was substantially damaged. The airplane was registered to and operated by a private individual under the provisions of 14 Code of Federal Regulations Part 91 as a personal flight. Visual meteorological conditions prevailed for the flight which operated without a flight plan. The local flight originated from 06C at 1200. According to the pilot, during the landing, the airplane's right wheel locked up. The airplane turned right, departed the runway, and collided with a taxiway sign. During the accident sequence, the main landing gear separated from the airplane. An examination of the airplane revealed substantial damage to the airplane's fuselage. A Federal Aviation Administration inspector responded to the accident scene. The inspector did not find any signs of tire scrubbing on the runway. In addition, no damage or worn spots were observed on the tire; the tire was able to freely rotate. No preimpact anomalies were detected on the airplane.