HISTORY OF FLIGHTOn August 30, 2020, about 1345 central daylight time, a Piper PA-24-250 airplane, N7469P, sustained substantial damage when it was involved in an accident near Bryan, Texas. The pilot and two passengers were fatally injured, and one passenger sustained serious injuries. The airplane was operated as a Title 14 Code of Federal Regulations Part 91 personal flight. According to a family member, the pilot had purchased the airplane about 2 weeks before the accident and the purpose of the flight was for the pilot to take his family members sightseeing in the local area. Security video footage at Coulter Field Airport (CFD), Bryan, Texas, showed that the airplane took off from runway 15; the video did not show the accident. The airplane wreckage was located crashed on a flat grass field off of the departure end of runway 15 on airport property. The surviving passenger was unable to recall any events from the accident. METEOROLOGICAL INFORMATIONThe calculated density altitude for the accident site was 3,205 ft. above mean sea level. WRECKAGE AND IMPACT INFORMATIONAn onsite examination of the airframe confirmed flight control continuity. The fuel tank selector handle was found in the right main position and was able to smoothly rotate through all the other positions with the detents plainly noted in each position. The right main fuel cell was visible from the wing root. The inboard forward portion of the right main fuel cell was observed with no tears or damage noted. Manual manipulation of the fuel cell did not reveal the presence of any usable fuel in what appeared to be the lowest portion of the fuel cell. A postaccident examination of the engine revealed no preimpact mechanical malfunctions or failures that would have precluded normal operation. The three bladed constant speed metal propeller remained attached at the crankshaft flange. The propeller blades remained attached to the propeller hub. Rotational signatures on the propeller were consistent with it not being driven at the time of impact. The pilot’s daughter posted three photographs of the airplane on social media before the flight. One photograph, taken by the daughter sitting in the front right seat, showed the right side of the instrument panel and included the fuel gauges. Based on the image, the following estimates were established regarding the airplane’s fuel status right before the accident: Left inboard fuel tank (main): About ¼ full. Left outboard fuel tank (auxiliary): Between ½ to ¾ full. Right inboard fuel tank (main): Between empty to ¼ full. Right outboard fuel tank (auxiliary): About ¾ full. ADDITIONAL INFORMATIONThe Piper PA-24-250 Owner’s Handbook discusses preflight inspection areas for the airplane. This document discusses the fuel tanks and states for the pilot to ensure that, “the fuel tanks are full or are at a safe level of proper fuel.” The Federal Aviation Administration (FAA) Pilot’s Handbook of Aeronautical Knowledge FAA-H-8083-25B discusses fuel quantity gauges and states in part: The fuel quantity gauges indicate the amount of fuel measured by a sensing unit in each fuel tank and is displayed in gallons or pounds. Aircraft certification rules require accuracy in fuel gauges only when they read “empty.” Any reading other than “empty” should be verified. Do not depend solely on the accuracy of the fuel quantity gauges. Always visually check the fuel level in each tank during the preflight inspection, and then compare it with the corresponding fuel quantity indication. MEDICAL AND PATHOLOGICAL INFORMATIONThe Travis County (Texas) Medical Examiner’s Office, Austin, Texas, performed the pilot’s autopsy. According to the autopsy report, the cause of death was blunt force injuries, and the manner of death was an accident. Toxicology testing performed by the Travis County Medical Examiner’s office was negative for tested-for substances, and a vitreous chemistry was unremarkable. The FAA Forensic Sciences Laboratory, Oklahoma City, Oklahoma, detected cetirizine in urine and at 216 nanograms per milliliter (ng/mL) in heart blood. Oxymetazoline was detected in urine but not heart blood. Cetirizine, sometimes marketed as Zyrtec, is an antihistamine medication that is available over the counter and is commonly used to treat allergy symptoms. The intended medicinal effects of cetirizine generally occur at blood cetirizine levels ranging from about 190 ng/mL to 1450 ng/mL. Cetirizine typically carries a warning that users may experience drowsiness and should be careful when driving a motor vehicle or operating machinery. Data on psychomotor impairment from cetirizine is mixed, with some studies, but not others finding mildly impairing effects. The FAA states that pilots should not fly within 48 hours of using cetirizine and should not use it more than 1-2 times per week. Oxymetazoline, sometimes marketed as Afrin, is a medication commonly used as a nasal decongestant spray. It is available over the counter and generally is not considered impairing.