On October 8, 2021, about 1904 Pacific daylight time, a Beech B36TC airplane, N7220B, was substantially damaged when it was involved in an accident near Los Banos, California. The pilot was not injured. The airplane was operated as a Title 14 Code of Federal Regulations Part 91 personal flight. The pilot reported that he flew the airplane to Paso Robles Municipal Airport (PRB), Paso Robles, California, where he refueled and was on his return flight to Gnoss Field Airport (DVO), Novato, California, when the accident occurred. The airplane was at about 10,000 ft mean sea level when the engine lost oil pressure and the manifold pressure dropped. He immediately diverted to Los Banos Municipal Airport (LSN), Los Banos, California. While in the descent into LSN, the engine was initially producing partial power, but then exhibited severe vibrations and subsequently lost all power. During this time, the cockpit filled with smoke, and fire and sparks were observed coming from the engine cowling. Due to the fire, the pilot elected to make a forced landing on a road near the approach end of the runway. The airplane struck an object during the landing roll, which caused the airplane to spin around before coming to rest. A review of engine data from a Garmin G500TXi device revealed that the airplane leveled off and the engine was set to about 2,500 rpm. About 9 minutes later, the engine’s oil pressure started to decrease, while the engine rpm was unchanged. In the next 12 minutes, the oil pressure continued to decrease and culminated with the engine rpm decreasing from about 2,371 to zero rpm in about 5 seconds while the airplane was in a descent. Postaccident examination of the engine revealed external damage with an exit hole on the crankcase near the top of the No. 2 cylinder. The hole was about 2 inches wide by 3 inches long. A second hole in the crankcase was noted on the left back side that had a diameter of about 1 inch. Additionally, several large cracks in the crankcase were observed on both crankcase halves. All engine accessories on the back side of the engine remained attached except for the left magneto. The rocker covers were removed and there was evidence of heat distress on all cylinders. Rotational continuity could not be established due to the crankshaft damage. Disassembly of the engine revealed that the No. 4 connecting rod bolt nut was missing. Thermal distress was observed in the area where the No. 4 connecting rod connected to the crankshaft, consistent with oil starvation. The thermal distress in this area was the most prominent in the engine. Considerable metal debris was noted in the oil sump and oil filter. The engine was installed in July of 2012, and logged about 671 hours of time before the accident. In June of 2020, the engine was disassembled for a propeller strike inspection. The inspection was about 27.3 hours before the accident. As part of the inspection, the connecting rods were overhauled by a third-party vendor, and then the vendor reinstalled the connecting rods on the crankshaft using new bearings, rod bolts, and nuts. The most recent annual inspection was accomplished in September of 2021, about 2.3 hours before the accident.