The pilot reported that he drove from his home to the airport not expecting to fly the helicopter due to high winds, however, after arrival at the hangar the winds were lighter than the forecast winds, so he conducted a preflight for a local flight. As the pilot raised the collective for takeoff and the helicopter climbed into an initial hover, the helicopter rolled to the left. The pilot tried to counter the roll but was unable because the cyclic control lock was still in place. The helicopter continued to roll left and impacted the ramp and a post impact fire ensued. The pilot successfully egressed the helicopter but suffered serious burn injuries. The helicopter sustained substantial damage to the main rotor system and the cabin. The pilot reported that there were no preaccident mechanical malfunctions or failures that would have precluded normal operation.