On June 14, 2025, about 1415 Alaska daylight time, a Stinson 108 airplane, N2101Q, was substantially damaged when it was involved in an accident near Cantwell, Alaska. The pilot and passenger sustained minor injuries. The airplane was operated as a Title 14 Code of Federal Regulations Part 91 personal flight. The pilot reported that there were no engine anomalies noted during the preflight inspection, pre-takeoff engine run-up checks or during the nearly two-hour flight from Fairbanks to the remote airstrip where he planned on doing touch-and-go landings. The landing on his second touch-and-go was uneventful, and then he initiated a go-around. The pilot reported feeling a shutter in the airplane as he applied full throttle and the airplane was not able to increase its airspeed for departure. There was not enough runway left to stop the airplane before it exited the end of the runway into brush and subsequently nosed over. The airplane sustained substantial damage to the fuselage, left wing, tail section and rudder. The airplane is being recovered for a post-accident examination.